NEAT1 was demonstrated to induce the expression of genes associated with viral infections such as IL8. Significantly, the NEAT1 binding splicing factor proline/glutamine-rich (SFPQ) appeared to repress IL8 expression; thus, NEAT1 was found to relocate SFPQ to the paraspeckles in order to remove SFPQ from the IL-8 promoter and initiate transcription of IL8 [100]. Here, CXCL8 is linked to viral infectious disease.