It also suppressed the inflammatory response in rats by reducing the levels of inducible nitric oxide synthase (iNOS), tumor necrosis factor alpha (TNF-α), and the interleukins, IL-1β and IL-6, in peritoneal exudate cells [22] and inhibited the inflammatory response in adults with hypercholesterolemia [7]. The gene discussed is TNF; the disease is familial hypercholesterolemia.