HNRNPA1 and amyotrophic lateral sclerosis: hnRNPA1 is also involved in many other processes necessary for cellular function including proliferation [68], mRNA splicing [69], and telomerase activity [70], and mutations in hnRNPA1 have been associated with human diseases including amyotrophic lateral sclerosis 20 [71], lung adenocarcinoma [72] and HIV-1 [73,74].