According to the database (cBioportal and UALCAN), the expression of ZFAS1 was significantly up-regulated in cancer samples of HNSCC patients compared to normal tissue (median expression of 226.109 vs. 175.467 transcripts per million; p = 2.24 × 10−14) (Figure 2A). Here, ZFAS1 is linked to head and neck squamous cell carcinoma.