CYP27A1 and nasopharyngeal carcinoma: Importantly, the initial metabolite of the conventional acidic pathway, (25R)26-hydroxycholesterol (26-HC), formed by CYP27A1 metabolism of cholesterol, was higher in NPB plasma samples (40–68 ng/mL) samples than NPC (12–16 ng/mL), LALD (7.5–11.5 ng/mL) or controls and carriers (16–28 ng/mL).