Furthermore, CTRP3 serum levels were higher in female compared with male in controls (380.12 ± 81.80 vs. 300.85 ± 65.15 ng/mL, p < 0.001) and T2DM-NP (256.57 ± 58.30 vs. 202.34 ± 35.93 ng/mL, p = 0.038) groups, however in T2DM group there was no significant difference (276.03 ± 90.95 vs. 245.09 ± 48.17 ng/mL, p = 0.65) (Fig 2b). Here, C1QTNF3 is linked to type 2 diabetes mellitus.