The main hematological and biochemical parameters monitored in clinical practice to predict dengue disease evolution are platelet and white blood cell (WBC) counts, hematocrit (HCT) and serum liver aminotransferases, both alanine and aspartate aminotransferases (ALT and AST), with thrombocytopenia, leukopenia, hematocrit increase >20% and elevated serum levels of AST/ALT being typical biological features of severe dengue in humans [30]. Here, GPT is linked to Decreased total leukocyte count.