PPARG and Alzheimer disease: infantis NCIMB 702255 (Bi702255) and a polyphenol rich polyphenol plant extract from the gastrointestinal tonic Triphala (TFLA) [15], can simultaneously impact several aspects of GBA signaling to prevent AD onset and delay its progression possibly through mechanisms implication peroxisome proliferator activated receptor (PPAR)γ.