INS and Insulin resistance: Hypertriglyceridemia and low HDL-C levels are 2 important metabolic abnormalities associated with insulin resistance.[28,29] Moreover, the TG/HDL-C ratio was proved to be a good and sensitive indicator to identify insulin-resistant individuals of North American aboriginal, Chinese, and European.[29] The TG/HDL-C ratio was considered as an atherogenic index.[30] In our study, we found that the TG/HDL-C ratio increased significantly throughout the pregnancy, which indicated progressive insulin resistance during normal pregnancy.