Discordance between positive ESR and CRP results is a recognised phenomenon and an evaluation of discordant ESR/CRP laboratory tests in adults indicated clinical differences, with infections, myocardial infarction and venous thrombosis more prevalent in the high CRP/low ESR group, and connective tissue disease, ischemic strokes and transient ischemic attacks more prevalent in the high ESR/low CRP group [22]. This evidence concerns the gene CRP and connective tissue disorder.