The second networks with a Z-score = 31 revealed the genes ATF7IP, CTNNB1, EIF2S3, FLG, FOXA1, FZD4, IKZF2, KCNN3, MACF1, PPFIBP2, PRDM15, PTPRD, SLC19A2, STAT3, TCF7L2, and TNS3 predicted to be involved in cancer, cellular development, and proliferation. The gene discussed is PRDM15; the disease is cancer.