Processes downregulated in ASD and upregulated in cancer included MYC targets, DNA repair, HIV infection and proteasome activity in 77%, 68%, 55%, and 46% of the studied cancers, respectively, whereas GPCR signaling and myogenesis are examples of pathways that were upregulated in ASD and downregulated in 59% and 63% of cancers, respectively (Fig. 3). This evidence concerns the gene MYC and HIV infectious disease.