These changes were more evident in kidney and thyroid cancers, where oxidative phosphorylation, mitochondrial electron transport chain and ATP synthesis-related genes, including ATP50, ATP5F1, OGDHL, ATP5J, CYC1, PFKM, UQCRFS1, NDUFB6, NDUFB2, NDUFAF1, NDUFV1, DLD, and COX7B, were found to be jointly downregulated with ASD. The gene discussed is CYC1; the disease is thyroid cancer.