To examine the effect of LCP1 knock down (KD) and dual ABCE1+ LCP1 KD on cell migration, we used shRNAs to stably underexpress ABCE1, LCP1, ABCE1+ LCP1, or scrambled in HS578 human breast cancer cells and 4T1 murine breast carcinoma cells. The gene discussed is ABCE1; the disease is breast carcinoma.