In particular, these included a germline single nucleotide variation (SNP: rs61755655) in exon 2 of the MLH3 gene (c.408T > C), related to Lynch syndrome and a single nucleotide variation (missense variants) (SNP: rs140825795) in the exon 1 of the RAD51D gene (c.26G > C; p.Cys9Ser), related to a form of hereditary cancer-predisposing syndrome, according to ClinVar database (https://www.ncbi.nlm.nih.gov/clinvar/) (Table 1). This evidence concerns the gene MLH3 and Lynch syndrome.