The survival analysis showed that four lncRNAs (MYCNOS, DLX6-AS1, LINC00221, and CRNDE) and two mRNAs (CCNB1 and SHCBP1) were prognostic biomarkers for patients with HCC in both the Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. This evidence concerns the gene CCNB1 and hepatocellular carcinoma.