Based on the results obtained from these pilot experiments, the non-effective doses of URB 597 (0.3 and 1 mg/kg) and JZL 184 (20 and 40 mg/kg) were then chosen for the next behavioral experiments evaluating the influence of these FAAH and MAGL inhibitors on the memory impairment, provoked by an acute injection of MK-801 (0.3 or 0.6 mg/kg), using the PA test in mice. Here, MGLL is linked to memory impairment.