Hongping Li at Shenzhen Children’s Hospital, Yuanfang Zhu at Bao’an Maternity and Child Health Hospital, and co-workers showed that low levels of a tumor-suppressing protein, Rho GTPase-activating protein 26 (ARHGAP26), promote the invasion and migration of ovarian cancer cells. The gene discussed is ARHGAP26; the disease is neoplasm.