These observations are consistent with other studies utilizing ROS-inducing agents with anti-cancer properties such as celastrol [132], HDAC inhibitors [133], penfluridol [134], piperlogumine [135], curcumin and other curcuminoids [136,137], CDDO-Me (a synthetic derivative of triterpenoid glycyrrhetinic acid) [138,139] and GT-094 (a nitric oxide-non-steroidal anti-inflammatory drug) [140]. The gene discussed is HDAC9; the disease is cancer.