A study by Cheng et al., 2016 showed an induced growth arrest in the G2/M phase by inhibiting the expression of Cyclin B1 and disruption of cyclin B1/CDC2 conjugate in cervical cancer cells exposed to SFN (6.25 μM, 12.5 μM and 25 μM) [94]. The gene discussed is CCNB1; the disease is cervical carcinoma.