These heterotypic clusters were detected in melanoma (Melanoma CTCs: CD45−/CD34−/CD90−/CD105−/CD73− but CD146+/MelA+ cells), as well as in breast cancer patients’ blood (Breast cancer CTCs: EpCAM+/PanCK+/DAPI+ but CD45− cells) [22]. This evidence concerns the gene ENG and breast cancer.