The mechanisms of infertility of Tsc22d3‐KO mice have been studied by several groups and in several strains (Bruscoli et al., 2012; La et al., 2018; Ngo, Beaulieu, et al., 2013; Ngo, Cheng, et al., 2013; Romero et al., 2012; Suarez et al., 2012). This evidence concerns the gene TSC22D3 and Infertility.