Mallea-Gil et al. followed 22 patients with microprolactinoma for a period between 4 and 192 months after CBG or bromocriptine suspension and found that only two patients needed to restart treatment for increasing PRL levels; among the remaining 20, a spontaneous reduction of PRL and a high rate of tumor disappearance at MRI were found [8]. The gene discussed is PRL; the disease is Microprolactinoma.