In line with this aim, we found that GSKJ4 treatment, as well as exposure to A-485, suppressed the viability of human T-ALL cell lines by promoting the accumulation of anti-proliferative factor p27 and related to apoptosis cleaved form of PARP and by suppressing protein levels of the oncogenic Notch target c-Myc (Figures 7C,D). Here, MYC is linked to acute lymphoblastic leukemia.