CD4 and hepatitis C virus infection: There were no statistically significant differences between ECLD and ECHD groups in terms of epidemiological (age, sex, and HIV-1 transmission), immunologic (absolute CD4+ and CD8+ T cells counts, %CD4 and CD4/CD8 ratio), genetic (HLA-B∗57/27 status) and virologic (plasma HIV-1 RNA, total HIV-1 DNA loads, and Hepatitis C status) characteristics at proviral diversity determination point or throughout the follow-up (Supplementary Table S1).