To unravel the effect of Akt phosphorylation in the course of infection, we assayed an allosteric Akt inhibitor (iAkt) which is isoform-selective against Akt 1 and Akt 2 and possesses high specificity compared to ATP-competitive inhibitors that also target closely related kinases due to similarities in catalytic domains (Pentassuglia et al., 2016; Ebner et al., 2017; Mousset et al., 2018). This evidence concerns the gene AKT1 and infection.