During that period, the TH deficiency associated with congenital hypothyroidism leads, in both rodent and humans, to defects in late neuron migration, cerebellar neuron and glia arborization and maturation (231–233), astrocyte and neuron differentiation in hippocampus (234–236), inhibitory neuron development and function (237, 238), oligodendrocyte differentiation and myelination (129, 239, 240), and synaptogenesis (241, 242). Here, TH is linked to congenital hypothyroidism.