NPPB and diabetes mellitus: Our data indicated that 1) compared to acute hyperglycemia and HbA1c, glycemic gap had greater discriminative power for predicting in-hospital mortality and the development of ARF in patients with diabetes admitted to the hospital due to AHF, and 2) incorporating glycemic gap could further increase the discriminative power of BNP, thus strengthening the clinical significance of glycemic gap in AHF.