In order to analyze the correlation between TRIM56 expression and breast cancer subtype markers, 141 breast tumor tissues were collected and immunohistochemistry (IHC) was applied to examine the protein levels of TRIM56, ER alpha, progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER2) (Fig. 1D). This evidence concerns the gene ERBB2 and breast neoplasm.