With respect to nephrotoxicity, genetic variants in organic cation transporter 2 (OCT2), (multidrug and toxin extrusion 1 (MATE1) and xeroderma pigmentosum group D (XPD), are believed to be of predictive value [21,22,23,24]. Here, SLC22A2 is linked to xeroderma pigmentosum-Cockayne syndrome complex.