Two studies revealed that CXCR3 and its ligand Mig were detected in the peripheral blood and lymphoma cells of the patients with gastric MALT lymphoma, suggesting that CXCR3 may be involved in the pathogenesis of neoplastic B cells that easily disseminate to the circulating systems and peripheral lymphoid organs [51,52]. This evidence concerns the gene CXCR3 and gastric mucosa-associated lymphoid tissue lymphoma.