Neoplastic cells of gastric MALT lymphoma cells are positive for surface Igs (most IgM, and less frequently IgG and IgA), CD43, Bcl-2, and complement receptors (CD21, CD35) [1,2,5,7,10], whereas CD5, CD23, and cyclin D1 immunostains are generally negative in MALT lymphoma cells [1,2,5,7,10], although rare cases of CD5-positive MALT lymphomas have been reported [11]. This evidence concerns the gene SPN and MALT lymphoma.