S100A8 and neoplasm: The clinical and biological significance of CagA in B-lymphocytes was further demonstrated in tumor samples of our 64 stage IE gastric MALT lymphoma patients, in which the CagA expression was higher in HP-dependent tumors (26/38 (68.4%)) than in HP-independent tumors (5/26 (19.2%), p < 0.001) [17].