Next, we examined in vivo contraction in the small intestine and despite no alteration at base line (Fig 5E and S5C Fig), we saw significantly delayed transit time following infection in Itgb8 (CD11c-Cre) mice, which was again rescued via the addition of rIL-17, but could not be restored by the adoptive transfer of Tregs (Fig 5D and 5E). This evidence concerns the gene ITGB8 and infection.