ITGB8 and infection: Indeed, beyond the previously reported initial baseline differences in intestinal Th17 cells in Itgb8 (CD11c-Cre) mice ([30] and (Fig 3D)), total small intestinal lamina propria IL-17+ CD4+ T-cell numbers failed to significantly increase following infection at day 13 p.i. in Itgb8 (CD11c-Cre) mice as compared to wild-types (Fig 2D).