Although there was no differences in tension either at baseline nor following carbachol treatment in naïve mice (S5B Fig and Fig 5C), following infection Itgb8 (CD11c-Cre) mice failed to significantly increase jejunal tension in response to stimulation with carbachol at day 13 p.i., as seen in in wild-type infected mice (Fig 5C and [23–25]). The gene discussed is ITGAX; the disease is infection.