SKP1 and viral infectious disease: In addition, Cotton leaf curl Multan virus betasatellite (CLCuMuB)-encoded βC1 protein can subvert plant ubiquitination through interacting with S-phase kinase-associated protein 1 (SKP1) to impair the integrity of the SKP1/Cullin1 (CUL1)/F-box (SCF) complex SCFCOI1, and thus promotes virus infection and symptom induction [38].