TLR9 and viral infectious disease: This diversity could be related to the phylogenetic associations between differentHPV species or with the interaction of different oncoproteins (E6, E7) with proteinsinvolved in apoptosis (it has been reported that different genotypes differentiallyincrease myc expression [51][52]) or E6, which cansuppress the transcription of TLR9 [53] or genes involved in interferon signaling (STAT), producing aninactivation state of the immune system and the inflammatory response associated tothe presence of the viral infection [54].