Macrophages present in lung tumors are M2 macrophages secreting anti‐inflammatory cytokines IL‐10 and TGF‐β, thereby promoting metastasis and angiogenesis.67, 68 These macrophages also produce mediators such as VEGF and COX‐PGE2 which also promotes tumor growth. The gene discussed is TGFB1; the disease is neoplasm.