Serum IL‐1α concentrations were statistically significantly lower in SSc patients with high serum creatinine (Supplementary table 3) and in SSc patients with low KCO than in those without (Figure 4a and Supplementary table 2), and serum IL‐1α concentrations were moderately positively correlated with KCO (Figure 4b). The gene discussed is IL1A; the disease is systemic sclerosis.