Contrary to this finding, IL‐1β was positively correlated with increased TR velocity, which is usually associated with an increased risk of PAH.30, 31 In light of these divergent results, and when considering the lack of correlation between serum IL‐1β and the presence of either ILD or PAH, a larger longitudinal study investigating the role of IL‐1β in SSc lung disease would be of considerable value. This evidence concerns the gene IL1B and lung disorder.