It was also found that a reduced expression of CD44, Nanog, Oct4, CXCL16 and EGFR after ST6GALNAC1 silencing in OCSCs indicated that CD90+ stem cells infected with miRNA against ST6GALNAC1 had weaker self-renewal capacity in ovarian cancer (Fig. 10). The gene discussed is POU5F1; the disease is ovarian cancer.