INS and Hypoglycemia: Wild-type and CX3CR1−/− mice displayed similar blood glucose levels in fed and fasted states, however fasted CX3CR1−/− mice did not develop hypoglycemia in response to insulin [blood glucose in C57BL/6: 2,02 ± 0,13 mM vs. CX3CR1−/−: 3,58 ± 0,45 mM; t(8) = 2.54, p = 0.035] (Fig. 7A).