Quantitative analysis of c-FOS positive cell nuclei confirmed significant hypoglycemia-induced increase in the paraventricular nucleus compared to fed [F (2, 6) = 10.05, p = 0.01; Bonferroni’s post hoc test, t(6) = 5.73, p < 0.05] and fasted mice [Bonferroni’s post hoc test, t(6) = 5.22, p < 0.05] (Fig. 1G,H). Here, FOS is linked to Hypoglycemia.