After the end of gene screening in the CFTR, a total of 63 variants were identified in the CF patients, and three patients had three variants as follow: (i) c.[1397C > A;3209G > A];[1624G > T]; (ii) c.[1521_1523delCTT];[1000C > T;1241A > C]; (iii) c.[3557delA];[1521_1523delCTT;3140-26A > G]. This evidence concerns the gene CFTR and cystic fibrosis.