Using the widely used M1 inflammatory cell markers CD80 and iNOs, we performed immunostaining of myocardium 48 and 72 h after MI and found that miR-19a/19b mimic-injected hearts display a substantial reduction in CD80 and iNOs signals (Fig. 5j, k), suggesting a reduction in M1-type inflammatory macrophages24–26. Here, CD80 is linked to myocardial infarction.