As shown in Fig. 1f, GBM patients (n = 420) with high ITGA2 expression demonstrated a significantly worse prognosis than the low ITGA2 group (n = 84, P = 0.002, log-rank test), indicating that ITGA2 may also serve as an important clinical biomarker of poor prognosis in GBM patients. The gene discussed is ITGA2; the disease is glioblastoma.