The mean EGABA in Scn1a+/− neurons was less depolarized than that of Scn1b−/− neurons over a similar time range (compare Fig. 7D vs. 4D), suggesting that these two DS models are similar but not identical and that the phenotype in Scn1b−/− brain is more severe than in Scn1a+/− brain. Here, SCN1B is linked to Dravet syndrome.