In cutaneous squamous cell carcinoma, Zhou et al. [23] unraveled that miR-365-targeted nuclear factor I/B transcriptionally repressed cyclin-dependent kinase 6 and 4 to inhibit the tumor progression, which was further consolidated by the observation that loss of BAX by miR-365 promoted cutaneous squamous carcinoma progression by suppressing apoptosis [24]. This evidence concerns the gene CDK6 and neoplasm.