At multiple regression analysis, we also observed a possible trend toward significance with regard to the protective role of HLA-A-Bw4 HLA alleles (p = 0.05) and of interaction between KIR 2DS2 and HLA-C2 alleles (p = 0.05) towards LAAS subtype of stroke (see Table 7). This evidence concerns the gene KIR3DL1 and Stroke.