TTN and familial dilated cardiomyopathy: Peters et al. [13] reported 11 genes associated with DCM and ventricular arrhythmias, including LMNA, sodium voltage-gated channel alpha subunit 5 (SCN5A), RNA binding motif protein 20 (RBM20), filamin C (FLNC), and TTN. In these populations, in which the mortality rate can be high, the implantable cardioverter-defibrillator (ICD) may provide benefit for the primary prevention of sudden cardiac death.