DSC2 and arrhythmogenic right ventricular cardiomyopathy: The autosomal dominant form that is common in ARVC includes five major genes: DSP, PKP2, DSG2, DSC2, and TMEM43. The autosomal recessive form of ARVC is less common, and involves mutations of the plakoglobin and desmoplakin genes (Naxos disease and Carvajal syndrome) [92,93,94].