Other studies suggested that the presence of either LKB1 (Algire et al., 2011, Shackelford et al., 2013) or AMPK (Jeon et al., 2012, Kishton et al., 2016) increased survival of tumor cells during nutrient or oxygen deprivation or oxidative stress, thus exerting tumor-promoting effects. Here, PRKAA1 is linked to neoplasm.