Upon LCMV infection, total numbers of endogenous CD8 T cells were increased in absence of NCR1, both in NCR1gfp/gfp mice and in C57BL/6 mice upon in vivo blocking of NCR1, using an αNCR1 antibody (ab) during infection (Fig 2B and S1A and S1B Fig). The gene discussed is CD8A; the disease is infection.