COLEC11 and heart failure: In addition, COLEC11*GGC was significantly associated with patients presenting ECHO alterations and with heart failure (p = 0.044, OR 2.2, 95% CI 1.0–4.6; and p = 0.033, OR 2.5, 95% CI 1.1–5.6 respectively) in comparison to controls (Table 5).