INS and Insulin resistance: Visceral fat accumulation is associated with insulin resistance and various metabolic complications.1 In this study, in which evaluation was based on blinded CT image measurement, administration of ipragliflozin resulted in reduced visceral fat area, even in combination with a DPP‐4i, an insulin secretagogue; by contrast, metformin combined with a DPP‐4i did not affect visceral fat area.