SERPING1 and hereditary angioedema: International consensus recommendations delineate acute treatment of HAE attacks in a pediatric population.10, 19 In principle, shorter time to treatment of attacks has been shown to improve clinical outcomes.19, 20 Despite progress made during the last decade with introduction of novel treatments for HAE, there is a paucity of evidence‐based treatment options for children.10 Recombinant human C1 esterase inhibitor (rhC1‐INH) is among the options for adults and adolescents.