MiR-7-5p acts as a tumor suppressor in pancreatic ductal adenocarcinoma and suppresses cell proliferation, migration and invasion by targeting SOX18 (Zhu et al., 2018); in MCF-10A mammary epithelial cells, this miRNA suppresses oncogenes by mediating the signaling of hepatocyte growth factor (Jeong et al., 2017). Here, SOX18 is linked to pancreatic ductal adenocarcinoma.