Bruck syndrome is an autosomal recessive disorder characterized by the combination of OI III and pterygium formation across large joints with resultant contractures and marked reduction in mobility.22 The condition is genetically heterogeneous with BS type 1 caused by mutations in FKBP10 and BS type 2, which is rare, caused by a mutation in PLOD2. These reports were orientated to the discussion of BS type 1 and 8 of these affected persons had contractures. This evidence concerns the gene FKBP10 and Bruck syndrome.